Description
Product Characteristics:
Aliases: C48 antibody, CDK5 activator-binding protein C48 antibody, CDK5 regulatory subunit associated protein 2 antibody, CDK5 regulatory subunit-associated protein 2 antibody, CDK5RAP2 antibody, centrosomal protein 215 kDa antibody, Centrosome-associated protein 215 antibody, CEP215 antibody, CK5P2_HUMAN antibody, MCPH3 antibody
Target Information: This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]